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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Julio [UNRATED] Urias# | 77 | 2021-2024 | |
| 2 | Jacob deGrom# | 72 | 2021-2024 | |
| 3 | Max Scherzer# | 71 | 2021-2024 | |
| 4 | Robbie Ray# | 69 | 2021-2024 | |
| 5 | Shane Bieber# | 61 | 2021-2024 | |
| 6 | Zac Gallen# | 47 | 2021-2024 | |
| 6 | Kevin Gausman# | 47 | 2021-2024 | |
| 6 | Logan Webb# | 47 | 2021-2024 | |
| 9 | Raisel Iglesias# | 44 | 2021-2024 | |
| 9 | Brandon Woodruff# | 44 | 2021-2024 | |
| 11 | Carlos Rodon# | 43 | 2022-2024 | |
| 12 | Liam Hendriks# | 42 | 2021-2024 | |
| 12 | Dustin May# | 42 | 2021-2024 | |
| 14 | Shane McClanahan# | 41 | 2022-2024 | |
| 15 | George Kirby# | 40 | 2023-2024 | |
| 16 | Max Fried# | 39 | 2021-2024 | |
| 17 | Trevor [UNRATED] Bauer | 32 | 2021-2022 | |
| 17 | Tyler Glasnow# | 32 | 2021-2024 | |
| 19 | Sandy Alcantara# | 31 | 2021-2024 | |
| 19 | Chris Bassitt# | 31 | 2021-2024 | |
| 19 | Aroldis Chapman# | 31 | 2021-2024 | |
| 19 | Lucas Giolito# | 31 | 2021-2024 | |
| 19 | Trevor Rogers# | 31 | 2022-2024 | |
| 19 | Justin Verlander# | 31 | 2021-2024 | |
| 25 | Walker Buehler# | 29 | 2021-2024 | |
| 25 | Shohei Ohtani# | 29 | 2021-2024 | |
| 27 | Luis Castillo# | 27 | 2021-2024 | |
| 27 | Joe Musgrove# | 27 | 2021-2024 | |
| 29 | Corbin Burnes# | 26 | 2021-2024 | |
| 29 | Dylan Cease# | 26 | 2022-2024 | |
| 29 | Gerrit Cole# | 26 | 2021-2024 | |
| 32 | Shane Baz# | 25 | 2022-2024 | |
| 33 | Tyler Anderson# | 23 | 2021-2024 | |
| 33 | Noah Syndergaard# | 23 | 2021-2024 | |
| 35 | Josh Hader# | 22 | 2021-2024 | |
| 35 | Patrick Sandoval# | 22 | 2021-2024 | |
| 37 | Griffin Canning# | 21 | 2021-2024 | |
| 37 | Logan Gilbert# | 21 | 2022-2024 | |
| 37 | Jonathan Loaisiga# | 21 | 2021-2024 | |
| 37 | Nick Lodolo# | 21 | 2022-2024 | |
| 37 | Triston McKenzie# | 21 | 2023-2024 | |
| 37 | Robert Stephenson# | 21 | 2021-2024 | |
| 43 | Jon Gray# | 20 | 2021-2024 | |
| 43 | Jordan Hicks# | 20 | 2021-2024 | |
| 43 | Kenley Jansen# | 20 | 2021-2024 | |
| 43 | Joe Jimenez# | 20 | 2023-2024 | |
| 43 | German Marquez# | 20 | 2021-2024 | |
| 43 | Charlie Morton# | 20 | 2021-2024 | |
| 49 | Tanner Houck# | 19 | 2022-2024 | |
| 49 | Aaron Nola# | 19 | 2021-2024 | |
| 49 | Jose Quintana# | 19 | 2021-2024 | |
| 52 | Giovanny Gallegos# | 18 | 2021-2024 | |
| 52 | Cristian Javier# | 18 | 2022-2024 | |
| 52 | Frankie Montas# | 18 | 2021-2024 | |
| 55 | Andres Muñoz# | 17 | 2021-2024 | |
| 55 | Marcus Stroman# | 17 | 2021-2024 | |
| 55 | Devin Williams# | 17 | 2021-2024 | |
| 58 | Jack Flaherty# | 16 | 2021-2024 | |
| 58 | Michael King# | 16 | 2021-2024 | |
| 58 | Cole Ragans# | 16 | 2024-2024 | |
| 58 | Jordan Romano# | 16 | 2022-2024 | |
| 58 | Steven Wilson# | 16 | 2023-2024 | |
| 63 | Ryan Helsley# | 15 | 2021-2024 | |
| 63 | Yusei Kikuchi# | 15 | 2021-2024 | |
| 63 | Hoby Milner# | 15 | 2021-2024 | |
| 63 | Jordan Montgomery# | 15 | 2021-2024 | |
| 63 | Reyes [UNRATED] Moronta# | 15 | 2021-2023 | |
| 63 | Evan Phillips# | 15 | 2023-2024 | |
| 63 | Ryan Pressly# | 15 | 2021-2024 | |
| 63 | Lucas Sims# | 15 | 2021-2024 | |
| 63 | Taijuan Walker# | 15 | 2021-2024 | |
| 72 | Sonny Gray# | 14 | 2021-2024 | |
| 72 | Clay Holmes# | 14 | 2022-2024 | |
| 72 | Wade Miley# | 14 | 2021-2024 | |
| 72 | Sean Reid-Foley# | 14 | 2021-2024 | |
| 72 | Chris Sale# | 14 | 2021-2024 | |
| 77 | Alex Cobb# | 13 | 2021-2024 | |
| 77 | Ian [UNRATED] Kennedy | 13 | 2021-2022 | |
| 77 | Chris Martin# | 13 | 2021-2024 | |
| 77 | David [UNRATED] Price | 13 | 2021-2022 | |
| 77 | A.J. Puk# | 13 | 2022-2024 | |
| 77 | Eduardo Rodriguez# | 13 | 2021-2024 | |
| 77 | Hyun-jin [UNRATED] Ryu# | 13 | 2021-2023 | |
| 77 | Craig [UNRATED] Stammen | 13 | 2021-2023 | |
| 77 | Jameson Taillon# | 13 | 2021-2024 | |
| 86 | Kolby Allard# | 12 | 2022-2024 | |
| 86 | Chris Devenski# | 12 | 2021-2021 | |
| 86 | Kevin Ginkel# | 12 | 2021-2024 | |
| 86 | Brusdar Graterol# | 12 | 2021-2024 | |
| 86 | Seth Lugo# | 12 | 2021-2024 | |
| 86 | Luis Severino# | 12 | 2021-2024 | |
| 92 | Austin Adams# | 11 | 2021-2022 | |
| 92 | Nathan Eovaldi# | 11 | 2021-2024 | |
| 92 | Luis Garcia# | 11 | 2023-2023 | |
| 92 | Mark Leiter# | 11 | 2024-2024 | |
| 92 | Tyler Mahle# | 11 | 2021-2024 | |
| 92 | Bryce Miller# | 11 | 2024-2024 | |
| 92 | Drew Rasmussen# | 11 | 2021-2024 | |
| 92 | Ryan Yarbrough# | 11 | 2021-2024 | |
| 100 | Diego Castillo# | 10 | 2021-2023 |
