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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jason Foley CL | 3 | 2 | 3 | 2.89 | 60 | 0 | 62.1 | 59 | 25 | 20 | 3 | 18 | 62 | 1.24 | .250 | .322 | 1.5 |
| Thomas Szapucki RP | 5 | 5 | 2 | 2.95 | 64 | 0 | 61.0 | 46 | 20 | 20 | 8 | 20 | 75 | 1.08 | .209 | .271 | 1.0 |
| Lucas Erceg CL | 5 | 2 | 4 | 3.18 | 64 | 0 | 70.2 | 55 | 27 | 25 | 8 | 30 | 67 | 1.20 | .213 | .255 | 0.5 |
| Ryan Pepiot RP | 10 | 7 | 0 | 3.38 | 26 | 26 | 136.0 | 115 | 58 | 51 | 21 | 51 | 154 | 1.22 | .225 | .278 | 1.9 |
| Brandon Pfaadt SP | 15 | 11 | 0 | 3.51 | 33 | 33 | 195.0 | 171 | 82 | 76 | 27 | 52 | 179 | 1.14 | .232 | .268 | 2.9 |
| Louie Varland RP | 5 | 5 | 2 | 3.59 | 62 | 0 | 92.2 | 65 | 38 | 37 | 15 | 31 | 90 | 1.04 | .196 | .216 | 0.2 |
| Jose Alvarado RP | 1 | 5 | 16 | 3.99 | 62 | 0 | 56.1 | 55 | 26 | 25 | 6 | 23 | 53 | 1.38 | .252 | .308 | 0.5 |
| Johan Oviedo RP | 2 | 0 | 0 | 4.08 | 37 | 0 | 57.1 | 66 | 26 | 26 | 10 | 16 | 61 | 1.43 | .289 | .354 | 0.2 |
| Drey Jameson RP | 1 | 1 | 2 | 4.32 | 39 | 0 | 50.0 | 46 | 24 | 24 | 6 | 15 | 47 | 1.22 | .242 | .286 | 0.4 |
| Spencer Schwellenbach SP | 12 | 11 | 0 | 4.46 | 35 | 35 | 211.2 | 211 | 110 | 105 | 28 | 56 | 208 | 1.26 | .254 | .306 | 3.8 |
| Aroldis Chapman CL | 1 | 1 | 0 | 4.98 | 31 | 0 | 21.2 | 26 | 12 | 12 | 6 | 12 | 27 | 1.75 | .299 | .364 | -0.7 |
| Gerrit Cole SP | 6 | 4 | 0 | 5.09 | 15 | 15 | 88.1 | 86 | 50 | 50 | 14 | 33 | 90 | 1.35 | .248 | .291 | 1.0 |
| Tyler Glasnow SP | 11 | 12 | 0 | 5.76 | 35 | 35 | 193.2 | 214 | 135 | 124 | 43 | 65 | 244 | 1.44 | .273 | .341 | 1.5 |
| Jack Flaherty RP | 7 | 5 | 0 | 6.00 | 36 | 18 | 117.0 | 115 | 82 | 78 | 27 | 41 | 133 | 1.33 | .256 | .297 | -0.0 |
| Justin Slaten CL | 1 | 0 | 1 | 7.62 | 23 | 0 | 26.0 | 22 | 22 | 22 | 4 | 19 | 26 | 1.58 | .232 | .273 | -0.2 |
| Josh Hader CL | 1 | 5 | 8 | 7.91 | 21 | 0 | 19.1 | 21 | 17 | 17 | 3 | 8 | 28 | 1.50 | .269 | .375 | 0.3 |
