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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Darren [UNRATED] O'Day | 2021-2022 | 1 | 7 | .125 | 5.42 | 73 | 0 | 0 | 0 | 1 | 76.1 | 85 | 46 | 5 | 30 | 76 |
| Tyler O'Neill | 2021-2024 | 0 | 0 | .000 | 81.00 | 1 | 0 | 0 | 0 | 0 | 0.1 | 2 | 3 | 0 | 3 | 0 |
| Bailey Ober | 2022-2024 | 23 | 26 | .469 | 4.85 | 101 | 84 | 0 | 0 | 0 | 454.2 | 444 | 245 | 78 | 126 | 425 |
| Scott Oberg | 2021-2022 | 7 | 3 | .700 | 2.49 | 105 | 1 | 0 | 0 | 7 | 122.2 | 102 | 34 | 10 | 25 | 122 |
| Rougned Odor | 2021-2022 | 0 | 0 | .000 | 0.00 | 1 | 0 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0 | 0 | 0 |
| Jake Odorizzi | 2021-2024 | 25 | 27 | .481 | 5.03 | 88 | 66 | 1 | 0 | 0 | 422.1 | 438 | 236 | 60 | 148 | 383 |
| Shohei Ohtani | 2021-2024 | 46 | 38 | .548 | 3.72 | 134 | 133 | 0 | 0 | 0 | 689.1 | 577 | 285 | 80 | 296 | 826 |
| Steven Okert | 2023-2024 | 4 | 3 | .571 | 4.96 | 128 | 0 | 0 | 0 | 6 | 98.0 | 97 | 54 | 13 | 60 | 115 |
| Jio Orozco | 2022-2022 | 4 | 3 | .571 | 6.43 | 75 | 0 | 0 | 0 | 0 | 77.0 | 102 | 55 | 16 | 47 | 75 |
| Oliver Ortega | 2024-2024 | 1 | 3 | .250 | 6.63 | 80 | 0 | 0 | 0 | 0 | 91.0 | 114 | 67 | 16 | 50 | 93 |
| Luis Ortiz | 2024-2024 | 0 | 0 | .000 | 5.40 | 1 | 1 | 0 | 0 | 0 | 5.0 | 4 | 3 | 2 | 4 | 4 |
| Roberto [UNRATED] Osuna | 2021-2022 | 10 | 7 | .588 | 3.13 | 108 | 0 | 0 | 0 | 4 | 120.2 | 101 | 42 | 14 | 20 | 119 |
| Adam Ottavino | 2021-2024 | 18 | 14 | .562 | 3.31 | 221 | 0 | 0 | 0 | 26 | 226.0 | 199 | 83 | 17 | 95 | 253 |
| Glenn Otto | 2022-2024 | 5 | 10 | .333 | 5.71 | 34 | 27 | 0 | 0 | 0 | 143.1 | 152 | 91 | 27 | 71 | 136 |
| Johan Oviedo | 2024-2024 | 0 | 4 | .000 | 4.46 | 72 | 0 | 0 | 0 | 1 | 103.0 | 83 | 51 | 12 | 47 | 88 |
