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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Darren [UNRATED] O'Day | 2021-2022 | .000 | 0 | 0 | 1 | 7 | 1 | 5.42 | 76 |
| Ryan O'Hearn | 2024-2024 | .240 | 30 | 76 | 0 | 0 | 0 | 0.00 | 0 |
| Logan O'Hoppe | 2023-2024 | .237 | 45 | 145 | 0 | 0 | 0 | 0.00 | 0 |
| Tyler O'Neill | 2021-2024 | .224 | 88 | 270 | 0 | 0 | 0 | 81.00 | 0 |
| Bailey Ober | 2022-2024 | .000 | 0 | 0 | 23 | 26 | 0 | 4.85 | 425 |
| Scott Oberg | 2021-2022 | .000 | 0 | 0 | 7 | 3 | 7 | 2.49 | 122 |
| Rougned Odor | 2021-2022 | .231 | 34 | 80 | 0 | 0 | 0 | 0.00 | 0 |
| Jake Odorizzi | 2021-2024 | .000 | 0 | 0 | 25 | 27 | 0 | 5.03 | 383 |
| Shohei Ohtani | 2021-2024 | .234 | 63 | 178 | 46 | 38 | 0 | 3.72 | 826 |
| Steven Okert | 2023-2024 | .000 | 0 | 0 | 4 | 3 | 6 | 4.96 | 115 |
| Jared Oliva | 2021-2021 | .182 | 0 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| Edward Olivares | 2024-2024 | .227 | 8 | 28 | 0 | 0 | 0 | 0.00 | 0 |
| Matt Olson | 2021-2024 | .260 | 152 | 440 | 0 | 0 | 0 | 0.00 | 0 |
| Jio Orozco | 2022-2022 | .000 | 0 | 0 | 4 | 3 | 0 | 6.43 | 75 |
| Oliver Ortega | 2024-2024 | .000 | 0 | 0 | 1 | 3 | 0 | 6.63 | 93 |
| Rafael Ortega | 2022-2024 | .250 | 22 | 105 | 0 | 0 | 0 | 0.00 | 0 |
| Joey Ortiz | 2024-2024 | .266 | 2 | 15 | 0 | 0 | 0 | 0.00 | 0 |
| Luis Ortiz | 2024-2024 | .000 | 0 | 0 | 0 | 0 | 0 | 5.40 | 4 |
| Roberto [UNRATED] Osuna | 2021-2022 | .000 | 0 | 0 | 10 | 7 | 4 | 3.13 | 119 |
| Adam Ottavino | 2021-2024 | .000 | 0 | 0 | 18 | 14 | 26 | 3.31 | 253 |
| Glenn Otto | 2022-2024 | .000 | 0 | 0 | 5 | 10 | 0 | 5.71 | 136 |
| James Outman | 2023-2024 | .233 | 48 | 146 | 0 | 0 | 0 | 0.00 | 0 |
| Johan Oviedo | 2024-2024 | .000 | 0 | 0 | 0 | 4 | 1 | 4.46 | 88 |
| Marcell Ozuna | 2021-2024 | .270 | 153 | 416 | 0 | 0 | 0 | 0.00 | 0 |
